Artemisinins target GABAA receptor signaling and impair α cell identity.

Artemisinins target GABAA receptor signaling and impair α cell identity.

Type 1 diabetes is characterized by the destruction of pancreatic beta cells, and generating new insulin-producing cells from other cell types is a major aim of regenerative medicine. One promising approach is transdifferentiation of developmentally related pancreatic cell types including...

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Hlavní autoři: Li, J, Casteels, T, Frogne, T, Ingvorsen, C, Honoré, C, Courtney, M, Huber, K, Schmitner, N, Kimmel, R, Romanov, R, Sturtzel, C, Lardeau, C, Klughammer, J, Farlik, M, Sdelci, S, Vieira, A, Avolio, F, Briand, F, Baburin, I, Májek, P, Pauler, F, Penz, T, Stukalov, A, Gridling, M, Parapatics, K, Barbieux, C, Berishvili, E, Spittler, A, Colinge, J, Bennett, K, Hering, S, Sulpice, T, Bock, C, Distel, M, Harkany, T, Meyer, D, Superti-Furga, G, Collombat, P, Hecksher-Sørensen, J, Kubicek, S
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2016

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