Investigations into the post-translational modification and mechanism of isopenicillin N:acyl-CoA acyltransferase using electrospray mass spectrometry.

Electrospray mass spectrometry (e.s.m.s.) was used to confirm the position of the post-translational cleavage of the isopenicillin N:acyl-CoA acyltransferase preprotein to give the alpha- and beta-subunits. The e.s.m.s. studies suggested partial modification of the alpha-subunit in vivo by exogenous...

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Bibliographic Details
Main Authors: Aplin, RT, Baldwin, J, Roach, P, Robinson, C, Schofield, C
Format: Journal article
Language:English
Published: 1993