Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy.

Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy.

Induction and maintenance of cytotoxic T lymphocyte (CTL) activity specific for a primary endogenous tumor was investigated in vivo. The simian virus 40 T antigen (Tag) expressed under the control of the rat insulin promoter (RIP) induced pancreatic beta-cell tumors producing insulin, causing progre...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Speiser, D, Miranda, R, Zakarian, A, Bachmann, M, McKall-Faienza, K, Odermatt, B, Hanahan, D, Zinkernagel, R, Ohashi, P
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	1997

समान संसाधन

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Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells.
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Identification of a cross-reactive self ligand in virus-mediated autoimmunity.
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T-cell-independent antiviral B cell responses in CD45-deficient mice.
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Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.
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Absence of co-stimulation and not the intensity of TCR signaling is critical for the induction of T cell unresponsiveness in vivo.
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Correction: Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy
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Functional management of an antiviral cytotoxic T-cell response.
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On the role of antigen in maintaining cytotoxic T-cell memory.
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Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen.
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T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction?
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Perspectives on Chimeric Antigen Receptor T-Cell Immunotherapy for Solid Tumors
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Antigen-Conjugated Silica Solid Sphere as Nanovaccine for Cancer Immunotherapy
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The influence of antigen organization on B cell responsiveness.
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Acute graft-versus-host disease without costimulation via CD28.
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Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.
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Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen.
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TNF receptor p55 mediates peripheral cytotoxic T cell deletion.
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Self-Tumor Antigens in Solid Tumors Turned into Vaccines by α-gal Micelle Immunotherapy
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Implications of Antigen Selection on T Cell-Based Immunotherapy
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High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
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Antigen-driven differentiation of naive Ig-transgenic B cells in vitro.
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Role of repetitive antigen patterns for induction of antibodies against antibodies.
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