Single point mutations in ATP synthase compensate for mitochondrial genome loss in trypanosomes

Viability of the tsetse fly-transmitted African trypanosome Trypanosoma brucei depends on maintenance and expression of its kinetoplast (kDNA), the mitochondrial genome of this parasite and a putative target for veterinary and human antitrypanosomatid drugs. However, the closely related animal patho...

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Detalhes bibliográficos
Main Authors: Dean, S, Gould, MK, Dewar, CE, Schnaufer, AC
Formato: Journal article
Idioma:English
Publicado em: National Academy of Sciences 2013