Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.
Recent multi-dimensional approaches to the study of complex disease have revealed powerful insights into how genetic and epigenetic factors may underlie their aetiopathogenesis. We examined genotype-epigenotype interactions in the context of Type 2 Diabetes (T2D), focussing on known regions of genom...
主要な著者: | Bell, C, Finer, S, Lindgren, C, Wilson, G, Rakyan, V, Teschendorff, A, Akan, P, Stupka, E, Down, T, Prokopenko, I, Morison, I, Mill, J, Pidsley, R, Deloukas, P, Frayling, T, Hattersley, A, McCarthy, M, Beck, S, Hitman, G |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2010
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