Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesion molecule-1.

The selectin family of cell adhesion molecules mediates the tethering and rolling of leukocytes on blood vessel endothelium. It has been postulated that the molecular basis of this highly dynamic adhesion is the low affinity and rapid kinetics of selectin interactions. However, affinity and kinetic...

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Bibliographic Details
Main Authors: Nicholson, M, Barclay, A, Singer, MS, Rosen, S, Van Der Merwe, P
Format: Journal article
Language:English
Published: 1998