α1-Acid glycoprotein reverses cocaine-induced sodium channel blockade in cardiac myocytes
α1-Acid glycoprotein (AAG) is an acute phase protein capable of binding basic drugs. This action explains its reversal of sodium channel blockade by drugs such as amitriptyline and quinidine. We report here the reversal of cocaine-induced sodium channel blockade by AAG. The sodium channel blocking p...
| Main Authors: | , , |
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| Format: | Journal article |
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Elsevier
2006
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