The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
<p>Two-pore-domain potassium (K<sub>2P</sub>) channels are key regulators of many physiological and pathophysiological processes and thus emerged as promising drug targets. As for other potassium channels, there is a lack of selective blockers, since drugs preferentially bind to a...
Main Authors: | , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
eLife Sciences Publications
2019
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