The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

<strong>Background<br></strong> Up to 80% of cases of prostate cancer present with multifocal independent tumour lesions leading to the concept of a field effect present in the normal prostate predisposing to cancer development. In the present study we applied Whole Genome DNA Sequ...

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Detalles Bibliográficos
Main Authors:	Buhigas, C, Warren, AY, Leung, W-K, Whitaker, HC, Luxton, HJ, Hawkins, S, Kay, J, Butler, A, Xu, Y, Woodcock, DJ, Merson, S, Frame, FM, Sahli, A, Abascal, F, Martincorena, I, Bova, GS, Foster, CS, Campbell, P, Maitland, NJ, Neal, DE, Massie, CE, Lynch, AG, Eeles, RA, Cooper, CS, Wedge, DC, Brewer, DS, Mills, IG
Outros autores:	CRUK-ICGC Prostate Cancer Group
Formato:	Journal article
Idioma:	English
Publicado:	BioMed Central 2022

The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

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