Structural premise of selective deubiquitinase USP30 inhibition by small-molecule benzosulfonamides
Dampening functional levels of the mitochondrial deubiquitylating enzyme USP30 has been suggested as an effective therapeutic strategy against neurodegenerative disorders such as Parkinson’s Disease. USP30 inhibition may counteract the deleterious effects of impaired turnover of damaged mitochondria...
| Main Authors: | , , , , , , , , , , |
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| Format: | Internet publication |
| Language: | English |
| Published: |
2022
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