Defective cholesterol metabolism in amyotrophic lateral sclerosis.

As neurons die cholesterol is released in the central nervous system (CNS), hence this sterol and its metabolites may represent a biomarker of neurodegeneration, including in amyotrophic lateral sclerosis (ALS) in which altered cholesterol levels have been linked to prognosis. More than 40 different...

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Bibliographic Details
Main Authors: Abdel-Khalik, J, Yutuc, E, Crick, P, Gustafsson, J, Warner, M, Roman, G, Talbot, K, Gray, E, Griffiths, W, Turner, M, Wang, Y
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016