Defective cholesterol metabolism in amyotrophic lateral sclerosis.
As neurons die cholesterol is released in the central nervous system (CNS), hence this sterol and its metabolites may represent a biomarker of neurodegeneration, including in amyotrophic lateral sclerosis (ALS) in which altered cholesterol levels have been linked to prognosis. More than 40 different...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology
2016
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