Nicotinamide cofactors suppress active-site labeling of aldehyde dehydrogenases
Active site labeling by (re)activity-based probes is a powerful chemical proteomic tool to globally map active sites in native proteomes without using substrates. Active site labeling is usually taken as a readout for the active state of the enzyme because labeling reflects the availability and reac...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Chemical Society
2016
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