A transcriptionally distinct CXCL13+ CD103+ CD8+ T-cell population is associated with B-cell 2 recruitment and neoantigen load in human cancer
The chemokine CXCL13 mediates recruitment of B cells to tumors and is essential for the formation of tertiary lymphoid structures (TLS). TLS are thought to support antitumor immunity and are associated with improved prognosis. However, it remains unknown whether TLS are formed in response to the...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Association for Cancer Research
2019
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