Structure of human complement C8, a precursor to membrane attack

Structure of human complement C8, a precursor to membrane attack

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Complement component C8 plays a pivotal role in the formation of the membrane attack complex (MAC), an important antibacterial immune effector. C8 initiates membrane penetration and coordinates MAC pore formation. High-resolution structures of C8 subunits have provided some insight into the function...

書誌詳細
主要な著者:	Bubeck, D, Roversi, P, Donev, R, Morgan, B, Llorca, O, Lea, S
フォーマット:	Journal article
言語:	English
出版事項:	Elsevier 2011
主題:	Pathology Biochemistry Genetics (medical sciences)

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