Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells

Effective adaptive immune responses require a large repertoire of naive T cells that migrate throughout the body, rapidly identifying almost any foreign peptide. Because the production of T cells declines with age, naive T cells must be long-lived. However, it remains unclear how naive T cells survi...

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Bibliographic Details
Main Authors: Mendoza, A, Fang, V, Chen, C, Serasinghe, M, Verma, A, Muller, J, Chaluvadi, V, Dustin, M, Hla, T, Elemento, O, Chipuk, J, Schwab, S
Format: Journal article
Language:English
Published: Springer Nature 2017