HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.

Chronic infections in mice can result in defects in memory CD8 T cell properties including low expression of the IL-7Ralpha (CD127). To determine whether defects in memory CD8 T cell formation exist during human chronic infections and to what extent these defects may be allele- or epitope-specific,...

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Bibliographic Details
Main Authors: Wherry, E, Day, C, Draenert, R, Miller, J, Kiepiela, P, Woodberry, T, Brander, C, Addo, M, Klenerman, P, Ahmed, R, Walker, B
Format: Journal article
Language:English
Published: 2006