HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.
Chronic infections in mice can result in defects in memory CD8 T cell properties including low expression of the IL-7Ralpha (CD127). To determine whether defects in memory CD8 T cell formation exist during human chronic infections and to what extent these defects may be allele- or epitope-specific,...
Main Authors: | Wherry, E, Day, C, Draenert, R, Miller, J, Kiepiela, P, Woodberry, T, Brander, C, Addo, M, Klenerman, P, Ahmed, R, Walker, B |
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Format: | Journal article |
Language: | English |
Published: |
2006
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