Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo

The T-box transcription factor (TF) Eomes is a key regulator of cell fate decisions during early mouse development. The cis-acting regulatory elements that direct expression in the anterior visceral endoderm (AVE), primitive streak (PS) and definitive endoderm (DE) have yet to be defined. Here, we i...

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Bibliographic Details
Main Authors: Simon, C, Downes, D, Gosden, M, Telenius, J, Higgs, D, Hughes, J, Costello, I, Bikoff, E, Robertson, E
Format: Journal article
Language:English
Published: Company of Biologists 2017