New hypothalamic hormone, corticotropin-releasing factor, specifically stimulates the release of adrenocorticotropic hormone and cortisol in man.

A synthetic preparation of the 41-aminoacid-residue peptide recently isolated from ovine hypothalami and characterised corticotropin-releasing factor (CRF), has been given intravenously to six normal men. 100 μg synthetic CRF caused rises in circulating levels of adrenocorticotropic hormone (ACTH) a...

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Bibliographic Details
Main Authors: Grossman, A, Kruseman, A, Perry, L, Tomlin, S, Schally, A, Coy, D, Rees, L, Comaru-Schally, A, Besser, G
Format: Journal article
Language:English
Published: 1982