Simulation studies of surrogate endpoint validation using single trial and multitrial statistical approaches.
OBJECTIVE: A schema was recently proposed for assessing the levels of evidence for surrogate validity that included 4 domains: Target, Study Design, Statistical Strength, and Penalties. This report examines one component of the schema. It surveys the literature on methods of statistical validation...
Main Authors: | , , , , , , |
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Format: | Conference item |
Published: |
2007
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