Adaption of neutral protease activity for islet isolation from the long-term two-layer method-stored pig pancreas.
BACKGROUND: Islet release from the pancreas is mediated by both collagenase and neutral protease (NP), a critical effector of islet integrity. To prove the hypothesis that adjustment of NP reduces islet damage after prolonged ischemia, adult pig pancreata were digested after 7-hour preservation by t...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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