Functional evaluation of smad4 disruption in mouse intestinal adenoma
<p>Human colorectal cancer (CRC) is one of the most common types of cancer. Aberrant activation of the Wnt pathway, typically via adenomatous polyposis coli (<em>Apc</em>) loss of function, acts as the initiating event for adenoma formation. However, alterations in additional pat...
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Formaat: | Thesis |
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2015
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