Functional evaluation of smad4 disruption in mouse intestinal adenoma

<p>Human colorectal cancer (CRC) is one of the most common types of cancer. Aberrant activation of the Wnt pathway, typically via adenomatous polyposis coli (<em>Apc</em>) loss of function, acts as the initiating event for adenoma formation. However, alterations in additional pat...

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Bibliografische gegevens
Hoofdauteur: Surakhy, M
Andere auteurs: Hassan, B
Formaat: Thesis
Gepubliceerd in: 2015