Bio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNA.

Across vertebrate genomes methylation of cytosine residues within the context of CpG dinucleotides is a pervasive epigenetic mark that can impact gene expression and has been implicated in various developmental and disease-associated processes. Several biochemical approaches exist to profile DNA met...

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Bibliographic Details
Main Authors: Blackledge, N, Long, H, Zhou, J, Kriaucionis, S, Patient, R, Klose, R
Format: Journal article
Language:English
Published: Oxford University Press 2012