Bio-CAP: a versatile and highly sensitive technique to purify and characterise regions of non-methylated DNA.
Across vertebrate genomes methylation of cytosine residues within the context of CpG dinucleotides is a pervasive epigenetic mark that can impact gene expression and has been implicated in various developmental and disease-associated processes. Several biochemical approaches exist to profile DNA met...
Main Authors: | Blackledge, N, Long, H, Zhou, J, Kriaucionis, S, Patient, R, Klose, R |
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Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2012
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