Towards a universally effective HLA-E-targeted HIV vaccine - a structural and biophysical exploration
Through major histocompatibility complex class I leader sequence-derived peptide (VL9) binding and CD94/NKG2 receptor engagement, human leucocyte antigen E (HLA-E) reports cellular health to NK cells. Previous studies demonstrated a strong bias for VL9 binding by HLA-E, a preference subsequently sup...
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| Format: | Thesis |
| Language: | English |
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2019
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