A phase II randomised controlled trial of amiloride as a neuroprotective treatment in optic neuritis – studying in vivo neurodegeneration, neuroprotection and cortical plasticity after an inflammatory insult to the visual system
<p>Basic science and early clinical trial evidence suggest the safe diuretic drug amiloride, may exert a neuroprotective effect in multiple sclerosis (MS) through blockade of the acid sensing ion channel. Neuroprotective treatments are a key unmet need in multiple sclerosis. Optic neuritis (ON...
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| Format: | Thesis |
| Language: | English |
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2017
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