[3H]GR113808 binding to serotonin 5-HT(4) receptors in the postmortem neocortex of Alzheimer disease: a clinicopathological study.

Abnormalities in neural transmission of serotonin (5-HT) may play a role in both cognitive and neuropsychiatric features of Alzheimer disease (AD). We measured 5-HT(4) receptors in the postmortem frontal and temporal cortex of 34 AD subjects and 15 controls by radioligand binding with [3H]GR113808....

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Bibliographic Details
Main Authors: Lai, M, Tsang, S, Francis, P, Esiri, M, Hope, T, Lai, O, Spence, I, Chen, C
Format: Journal article
Language:English
Published: 2003