DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

Randomised controlled trials are considered to be the best method to assess comparative clinical efficacy and effectiveness, and can be a key source of data for estimating cost effectiveness. Central to the design of a randomised controlled trial is an a priori sample size calculation, which ensures...

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Bibliographic Details
Main Authors: Cook, J, Julious, S, Sones, W, Hampson, L, Hewitt, C, Berlin, J, Ashby, D, Emsley, R, Fergusson, D, Walters, S, Wilson, E, Maclennan, G, Stallard, N, Rothwell, J, Bland, M, Brown, L, Ramsay, C, Cook, A, Armstrong, D, Altman, D, Vale, L
Format: Journal article
Published: BMJ Publishing Group 2018