ISOPENICILLIN-N SYNTHASE - A NEW MODE OF REACTIVITY
Incubation of L-δ-(α-aminoadipoyl)-L-(3,3-difluorohomocysteinyl)-D-valine [an analogue of the natural substrate: L-δ-(α-aminoadipoyl)-L-(cysteinyl)-D-valine] with isopenicillin N synthase (IPNS) resulted in the production of a thiocarboxylic acid, i.e. both equivalents of the dioxygen cosubstrate we...
| Main Authors: | , , |
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| Format: | Journal article |
| Published: |
1992
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