Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes

Chronic hepatitis B, C, and D virus (HBV, HCV, and HDV) infections are the leading causes of liver disease and cancer worldwide. Recently, the solute carrier and sodium taurocholate co-transporter NTCP has been identified as a receptor for HBV and HDV. Here, we uncover NTCP as a host factor regulati...

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Bibliographic Details
Main Authors: Verrier, E, Colpitts, C, Bach, C, Heydmann, L, Zona, L, Xiao, F, Thumann, C, Crouchet, E, Gaudin, R, Sureau, C, Cosset, F, McKeating, J, Pessaux, P, Hoshida, Y, Schuster, C, Zeisel, M, Baumert, T
Format: Journal article
Language:English
Published: Cell Press 2016