The second United Kingdom Heart and Renal Protection (UK-HARP-II) Study: a randomized controlled study of the biochemical safety and efficacy of adding ezetimibe to simvastatin as initial therapy among patients with CKD.

BACKGROUND: Evaluating the effects of decreasing low-density lipoprotein (LDL) cholesterol levels requires large randomized trials. In preparation for such a trial, we assessed the biochemical efficacy, safety, and tolerability of adding ezetimibe, 10 mg/d, to simvastatin, 20 mg/d, as initial therap...

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Bibliographic Details
Main Authors: Landray, M, Baigent, C, Leaper, C, Adu, D, Altmann, P, Armitage, J, Ball, S, Baxter, A, Blackwell, L, Cairns, H, Carr, S, Collins, R, Kourellias, K, Rogerson, M, Scoble, J, Tomson, C, Warwick, G, Wheeler, D
Format: Journal article
Language:English
Published: 2006