Actions of aprataxin in multiple DNA repair pathways.
Mutations in the Aptx gene lead to a neurological disorder known as ataxia oculomotor apraxia-1. The product of Aptx is Aprataxin (Aptx), a DNA-binding protein that resolves abortive DNA ligation intermediates. Aprataxin catalyzes the nucleophilic release of adenylate groups covalently linked to 5&#...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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