Studies of isopenicillin N synthase enzymatic properties using a continuous spectrophotometric assay.

Isopenicillin N synthase (IPNS) from Aspergillus nidulans is a no-heme iron(II)-dependent oxygenase which catalyses, in a single reaction, the bicyclisation of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine into isopenicillin N, the precursor of all other penicillins, cephalosporins and cephamyci...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Dubus, A, Sami, M, Brown, T, Schofield, C, Baldwin, J, Frère, J
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2000