Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263-272, KRWIILGLNK). Substitution of lysine (K) or glycine (G) for arginine (R) at HIV-1 gag residue 264 (R264...
Үндсэн зохиолчид: | Kelleher, A, Long, C, Holmes, E, Allen, R, Wilson, J, Conlon, C, Workman, C, Shaunak, S, Olson, K, Goulder, P, Brander, C, Ogg, G, Sullivan, J, Dyer, W, Jones, I, Mcmichael, A, Rowland-Jones, S, Phillips, R |
---|---|
Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2001
|
Ижил төстэй зүйлс
Ижил төстэй зүйлс
-
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses
-н: Kelleher, A, зэрэг
Хэвлэсэн: (2001) -
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
-н: Schneidewind, A, зэрэг
Хэвлэсэн: (2007) -
HIV-1 Escape from an HLA-B*13-Restricted Gag Epitope Affects the Gag-Pol Frameshift Stem-loop and Reduces Viral Fitness
-н: Prado, J, зэрэг
Хэвлэсэн: (2008) -
Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection.
-н: Wilson, J, зэрэг
Хэвлэсэн: (2000) -
HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins
-н: Brumme, Zabrina L., зэрэг
Хэвлэсэн: (2010)