Interactions between hypoxia and hypercapnic acidosis on calcium signaling in carotid body type I cells.

The effects of hypercapnic acidosis and hypoxia on intracellular Ca(2+) concentration ([Ca(2+)](i)) were determined with Indo 1 in enzymatically isolated single type I cells from neonatal rat carotid bodies. Type I cells responded to graded hypoxic stimuli with graded [Ca(2+)](i) rises. The percenta...

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Bibliographic Details
Main Authors: Dasso, L, Buckler, K, Vaughan-Jones, R
Format: Journal article
Language:English
Published: 2000