Influence of neutral protease activity on human islet isolation outcome.

Observations in rat pancreata have revealed that enzymatic islet release is mediated by both collagenase and neutral protease (NP), a critical effector of islet integrity. Since no information is available about the effect of NP activity on islet release from the human pancreas, the present study ev...

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Bibliographic Details
Main Authors: Brandhorst, H, Brendel, MD, Eckhard, M, Bretzel, R, Brandhorst, D
Format: Journal article
Language:English
Published: 2005