Early antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cells.

CD8(+) T cells are major players in antiviral immunity against human immunodeficiency virus type 1 (HIV-1) through recognition of viral epitopes presented on the surface of infected cells. However, the early events involving HIV-1 epitope presentation to CD8(+) T cells remain poorly understood but a...

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Bibliographic Details
Main Authors: Kløverpris, H, Payne, R, Sacha, J, Rasaiyaah, J, Chen, F, Takiguchi, M, Yang, O, Towers, G, Goulder, P, Prado, J
Format: Journal article
Language:English
Published: 2013