How homologous recombination maintains telomere integrity

Telomeres protect the ends of linear chromosomes against loss of genetic information and inappropriate processing as damaged DNA and are therefore crucial to the maintenance of chromosome integrity. In addition to providing a pathway for genome-wide DNA repair, homologous recombination (HR) plays a...

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Bibliographic Details
Main Authors: Tacconi, E, Tarsounas, M
Format: Journal article
Published: Springer Berlin Heidelberg 2015