Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study
<p><strong>OBJECTIVE:</strong> There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type...
| Glavni autori: | , , , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
American Diabetes Association
2020
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| _version_ | 1826282238061314048 |
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| author | Ibsen, DB Imamura, F Steur, M Papier, K Tong, Y |
| author_facet | Ibsen, DB Imamura, F Steur, M Papier, K Tong, Y |
| author_sort | Ibsen, DB |
| collection | OXFORD |
| description | <p><strong>OBJECTIVE:</strong> There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact.</p>
<p><strong>RESEARCH DESIGN AND METHODS:</strong> The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals with type 2 diabetes and a subcohort of 15,450 participants in eight countries. We modeled the replacement of self-reported red and processed meat with poultry, fish, eggs, legumes, cheese, cereals, yogurt, milk, and nuts. Country-specific hazard ratios (HRs) for incident type 2 diabetes were estimated by Prentice-weighted Cox regression and pooled using random-effects meta-analysis.</p>
<p><strong>RESULTS:</strong> There was a lower hazard for type 2 diabetes for the modeled replacement of red and processed meat `(50 g/day) with cheese (HR 0.90, 95% CI 0.83–0.97) (30 g/day), yogurt (0.90, 0.86–0.95) (70 g/day), nuts (0.90, 0.84–0.96) (10 g/day), or cereals (0.92, 0.88–0.96) (30 g/day) but not for replacements with poultry, fish, eggs, legumes, or milk. If a causal association is assumed, replacing red and processed meat with cheese, yogurt, or nuts could prevent 8.8%, 8.3%, or 7.5%, respectively, of new cases of type 2 diabetes.</p>
<p><strong>CONCLUSIONS:</strong> Replacement of red and processed meat with cheese, yogurt, nuts, or cereals was associated with a lower rate of type 2 diabetes. Substituting red and processed meat by other protein sources may contribute to the prevention of incident type 2 diabetes in European populations.</p> |
| first_indexed | 2024-03-07T00:40:49Z |
| format | Journal article |
| id | oxford-uuid:82f9ef0e-1423-48e6-82c0-db725cfba4ff |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:40:49Z |
| publishDate | 2020 |
| publisher | American Diabetes Association |
| record_format | dspace |
| spelling | oxford-uuid:82f9ef0e-1423-48e6-82c0-db725cfba4ff2022-03-26T21:41:10ZReplacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:82f9ef0e-1423-48e6-82c0-db725cfba4ffEnglishSymplectic ElementsAmerican Diabetes Association2020Ibsen, DBImamura, FSteur, MPapier, KTong, Y<p><strong>OBJECTIVE:</strong> There is sparse evidence for the association of suitable food substitutions for red and processed meat on the risk of type 2 diabetes. We modeled the association between replacing red and processed meat with other protein sources and the risk of type 2 diabetes and estimated its population impact.</p> <p><strong>RESEARCH DESIGN AND METHODS:</strong> The European Prospective Investigation into Cancer (EPIC)-InterAct case cohort included 11,741 individuals with type 2 diabetes and a subcohort of 15,450 participants in eight countries. We modeled the replacement of self-reported red and processed meat with poultry, fish, eggs, legumes, cheese, cereals, yogurt, milk, and nuts. Country-specific hazard ratios (HRs) for incident type 2 diabetes were estimated by Prentice-weighted Cox regression and pooled using random-effects meta-analysis.</p> <p><strong>RESULTS:</strong> There was a lower hazard for type 2 diabetes for the modeled replacement of red and processed meat `(50 g/day) with cheese (HR 0.90, 95% CI 0.83–0.97) (30 g/day), yogurt (0.90, 0.86–0.95) (70 g/day), nuts (0.90, 0.84–0.96) (10 g/day), or cereals (0.92, 0.88–0.96) (30 g/day) but not for replacements with poultry, fish, eggs, legumes, or milk. If a causal association is assumed, replacing red and processed meat with cheese, yogurt, or nuts could prevent 8.8%, 8.3%, or 7.5%, respectively, of new cases of type 2 diabetes.</p> <p><strong>CONCLUSIONS:</strong> Replacement of red and processed meat with cheese, yogurt, nuts, or cereals was associated with a lower rate of type 2 diabetes. Substituting red and processed meat by other protein sources may contribute to the prevention of incident type 2 diabetes in European populations.</p> |
| spellingShingle | Ibsen, DB Imamura, F Steur, M Papier, K Tong, Y Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title | Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title_full | Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title_fullStr | Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title_full_unstemmed | Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title_short | Replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in European populations; the EPIC-InterAct study |
| title_sort | replacement of red and processed meat with other food sources of protein and the risk of type 2 diabetes in european populations the epic interact study |
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