Glucocorticosteroids as dengue therapeutics: resolving clinical observations with a primary human macrophage model.

A recent trial [1] investigated the use of a glucocorticosteroid, prednisolone, as a therapy for reduction of severe dengue disease. Many pathogens induce accelerated or excessive inflammation, resulting in detrimental rather than protective effects [2], and dengue virus is a well-characterized exam...

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Bibliografische gegevens
Hoofdauteurs: Sayce, A, Miller, J, Zitzmann, N
Formaat: Journal article
Taal:English
Gepubliceerd in: Oxford University Press 2012