A polymorphism in human MR1 is associated with mRNA expression and susceptibility to tuberculosis.
The MR1 antigen-presenting system is conserved among mammals and enables T cells to recognize small molecules produced by bacterial pathogens, including Mycobacterium tuberculosis (M.tb). However, it is not known if MR1-mediated antigen presentation is important for protective immunity against myco...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Nature Publishing Group
2016
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