A physical-organic approach to asymmetric catalysis: design and synthesis of chiral ligands using multivariate modelling

<p>Discovery of new asymmetric metal-catalyzed transformations is closely related to the development of efficient and robust chiral ligands, such that ligand optimisation is a crucial step in reaction development but its success is highly uncertain. Mostly based on trial-and-error, such a daun...

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Bibliographic Details
Main Author: Brethome, A
Other Authors: Fletcher, S
Format: Thesis
Language:English
Published: 2020
Subjects: