Targeting the IGF receptor as treatment for cancer

Targeting the IGF receptor as treatment for cancer

Bibliografiske detaljer
Hovedforfatter:	Macaulay, V
Format:	Journal article
Udgivet:	2007

Lignende værker

The IGF receptor as anticancer treatment target.
af: Macaulay, V
Udgivet: (2004)

Development of molecular agents for IGF receptor targeting.
af: Salisbury, A, et al.
Udgivet: (2003)

Dual silencing of the EGF and type 1 IGF receptors suggests dominance of IGF signaling in human breast cancer cells.
af: Riedemann, J, et al.
Udgivet: (2007)

Therapeutic targeting of the IGF axis
af: Osher, E, et al.
Udgivet: (2019)

Therapeutic Targeting of the IGF Axis
af: Eliot Osher, et al.
Udgivet: (2019-08-01)

Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling
af: Qureishi, A, et al.
Udgivet: (2019)

Insulin-like growth factor (IGF) pathway targeting in cancer: role of the IGF axis and opportunities for future combination studies
af: Simpson, A, et al.
Udgivet: (2017)

The EGF receptor interacts with the type 1 IGF receptor and regulates its stability.
af: Riedemann, J, et al.
Udgivet: (2007)

Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression.
af: Turney, B, et al.
Udgivet: (2011)

Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.
af: Brierley, G, et al.
Udgivet: (2010)

The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript.
af: Bohula, E, et al.
Udgivet: (2003)

PL6 biology of the IGF1R
af: Macaulay, V
Udgivet: (2008)

Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer.
af: Yuen, J, et al.
Udgivet: (2008)

IGF1R INHIBITORS: RATIONAL COMBINATORIAL STRATEGIES
af: Macaulay, V
Udgivet: (2010)

IGF1R signalling and its inhibition.
af: Riedemann, J, et al.
Udgivet: (2006)

Targeting the type 1 insulin-like growth factor receptor as anti-cancer treatment.
af: Bohula, E, et al.
Udgivet: (2003)

Insulin like growth factor receptor 1 (IGF-1R) and radiotherapy resistance in laryngeal squamous cell cancer (LSCC)
af: Qureishi, A, et al.
Udgivet: (2018)

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.
af: Imrie, H, et al.
Udgivet: (2012)

Does the IGF-1R have a role in the DNA damage response?
af: Macaulay, V
Udgivet: (2012)

Human melanoma cells expressing V600E B-RAF are susceptible to IGF1R targeting by small interfering RNAs.
af: Yeh, A, et al.
Udgivet: (2006)

Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma
af: Simpson, A, et al.
Udgivet: (2019)

Targeting the IGF-Axis for Cancer Therapy: Development and Validation of an IGF-Trap as a Potential Drug
af: Yinhsuan Michely Chen, et al.
Udgivet: (2020-04-01)

The Role of Nuclear Insulin and IGF1 Receptors in Metabolism and Cancer
af: Haim Werner, et al.
Udgivet: (2021-04-01)

Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targets
af: Yinqi Zhang, et al.
Udgivet: (2021-11-01)

Lessons Learned from Targeting IGF-I Receptor in Thyroid-Associated Ophthalmopathy
af: Joseph A.M.J.L. Janssen, et al.
Udgivet: (2021-02-01)

Depletion of the type 1 IGF receptor delays repair of radiation-induced DNA double strand breaks
af: Turney, B, et al.
Udgivet: (2012)

Targeting IGF perturbs global replication through ribonucleotide reductase dysfunction
af: Rieunier, G, et al.
Udgivet: (2021)

Type 1 insulin-like growth factor receptor (IGF-1R) targeted therapies in pediatric cancer
af: Michael J Wagner, et al.
Udgivet: (2013-02-01)

Revisiting the IGF-1R as a breast cancer target
af: Roudy Chiminch Ekyalongo, et al.
Udgivet: (2017-05-01)

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice
af: Kai Mao, et al.
Udgivet: (2018-06-01)

IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718.
af: Mie Andersen, et al.
Udgivet: (2017-01-01)

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
af: Yosuke Yoneyama, et al.
Udgivet: (2018-04-01)

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.
af: Clair L Alvino, et al.
Udgivet: (2011-01-01)

How IGF-1 activates its receptor
af: Jennifer M Kavran, et al.
Udgivet: (2014-09-01)

Insulin-like growth factor 1 receptor (IGF-1R) as a target of MiR-497 and plasma IGF-1R levels associated with TNM stage of pancreatic cancer.
af: Jian-Wei Xu, et al.
Udgivet: (2014-01-01)

Understanding the key to targeting the IGF axis in cancer: a biomarker assessment
af: Kunal Amratlal Lodhia, et al.
Udgivet: (2015-07-01)

The IGF hormonal network in endometrial cancer: functions, regulation and targeting approaches
af: Ilan eBruchim, et al.
Udgivet: (2014-05-01)

PPAR-γ Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer
af: A. Belfiore, et al.
Udgivet: (2009-01-01)

Discoidin Domain Receptor 1 functionally interacts with the IGF-I system in bladder cancer
af: Simone Buraschi, et al.
Udgivet: (2020-05-01)

Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer
af: Rochester, M, et al.
Udgivet: (2005)