Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

The finding that the metazoan hypoxic response is regulated by oxygen-dependent posttranslational hydroxylations, which regulate the activity and lifetime of hypoxia-inducible factor (HIF), has raised the question of whether other hydroxylases are involved in the regulation of gene expression. We re...

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Bibliographic Details
Main Authors: Webby, C, Wolf, A, Gromak, N, Dreger, M, Kramer, H, Kessler, B, Nielsen, M, Schmitz, C, Butler, D, Yates, JR, Delahunty, C, Hahn, P, Lengeling, A, Mann, M, Proudfoot, N, Schofield, C, Böttger, A
Format: Journal article
Language:English
Published: 2009

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