Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia

<p>CONTEXT: The classic androgen synthesis pathway proceeds via DHEA, androstenedione and testosterone to 5α-dihydrotestosterone (DHT). However, DHT synthesis can also be achieved by an alternative pathway originating from 17α-hydroxyprogesterone (17OHP), which accumulates in congenital adrena...

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Bibliographic Details
Main Authors: Jones, C, Mallappa, A, Reisch, N, Nikolaou, N, Krone, N, Hughes, B, O'Neil, D, Whitaker, M, Tomlinson, J, Storbeck, K, Merke, D, Ross, R, Arlt, W
Format: Journal article
Language:English
Published: Endocrine Society 2016