The centrosome and the DNA damage induced checkpoint.

The centrosome, the microtubule-organizing center of the cell, acts as a localization point, where signaling molecules are able to interact. Many kinases and phosphatases critical for regulation of DNA damage signaling pathways localize to the centrosome. This review will discuss the possible involv...

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Bibliographic Details
Main Authors: Fletcher, L, Muschel, R
Format: Journal article
Language:English
Published: 2006