Structural basis for GABAA receptor potentiation by neurosteroids

Type A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of inhibitory neurotransmission in the human brain. Endogenous neurosteroids interact with GABAARs to regulate acute and chronic anxiety and are potent sedative, analgesic, anticonvulsant and anesthetic agents. Their mode of...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Miller, P, Scott, S, Masiulis, S, De Colibus, L, Pardon, E, Steyaert, J, Aricescu, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Springer Nature 2017