Structural basis for GABAA receptor potentiation by neurosteroids
Type A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of inhibitory neurotransmission in the human brain. Endogenous neurosteroids interact with GABAARs to regulate acute and chronic anxiety and are potent sedative, analgesic, anticonvulsant and anesthetic agents. Their mode of...
Egile Nagusiak: | Miller, P, Scott, S, Masiulis, S, De Colibus, L, Pardon, E, Steyaert, J, Aricescu, A |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
Springer Nature
2017
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