Stem cell modelling of ⍺-synuclein aggregation and its pathology
⍺-Synuclein is a key player in the pathogenesis of Parkinson’s disease and related disorders, yet it remains unclear how its aggregation triggers the degeneration of human dopaminergic neurons. In this study, I induced ⍺-synuclein aggregation in human iPSC-derived dopaminergic neurons using ⍺-synucl...
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| Format: | Thesis |
| Language: | English |
| Published: |
2021
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