Dimerization of arginyl-tRNA synthetase by free heme drives its inactivation in plasmodium falciparum
Excess cellular heme is toxic, and malaria parasites regulate its levels during hemoglobin digestion. Aminoacyl-tRNA synthetases are ubiquitous enzymes, and of these, arginyl-tRNA synthetase (RRS) is unique as its enzymatic product of charged tRNA is required for protein synthesis and degradation. W...
| Үндсэн зохиолчид: | , , |
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| Формат: | Journal article |
| Хэвлэсэн: |
Cell Press
2016
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